On Thursday, 31 January 2013, the Charles Rodolphe Brupbacher Prize will be awarded for the 11th time to a scientist for outstanding achievements in cancer research. This year’s award goes to Michael Karin, professor in the Department of Pharmacology at the University of California in San Diego.
Michael Karin is one of the most cited authors in biomedical science. He made a name for himself with his fundamental studies on the role of chronic inflammation in tumor development, such as hepatic cancer following an infection with the hepatitis B or C viruses or stomach cancer through an infection with the gastric bacterium Helicobacter pylori. A specific viral or bacterial pathogen, however, is not necessary because any chronic inflammatory damage to the intestinal mucosa carries a significantly increased risk of colon cancer. This includes immunologically induced inflammatory bowel diseases.
Evidence of causal link between inflammation and carcinogenesis
Karin is an internationally renowned expert on signaling pathways, transduction pathways that enable cells to respond to external influences. Karin is particularly interested in the influence of stress and infections. He showed how the cell’s normal signaling pathways can go awry in the event of chronic infections, with cancer as a possible consequence.
Michael Karin’s work has greatly advanced our understanding of the molecular basis of tumour development and is of vital importance in devising new strategies for prevention and therapy.
Public lecture by Gottfried Schatz and prizes for young scientists
On the eve of the award ceremony, the Brupbacher Foundation is holding a public lecture by Professor Gottfried Schatz entitled “Die tragische Substanz. Wie genetische Fehler Alterung und Krebs bewirken”. Schatz is emeritus professor of the University of Basel and a biochemist of international standing – especially in the field of mitochondria, the energy-providing powerhouses in the cell.
The last item on the symposium’s program is devoted to young scientists: Up to five junior researchers will receive a Young Investigator Award at the conclusion of the symposium on Friday morning.
nullProgram Overview null nullnullnull11th Charles Rodolphe Brupbacher Symposium «Breakthroughs in Cancer Research and Therapy» null30 January to 1 February 2013 nullUniversity Hospital Zurich, Hörsaal Ost, Gloriastrasse 29, 8091 Zurich nullIn English; Registration (free of charge): www.brupbacher-foundation.org null nullnullnullPublic Lecture nullGottfried Schatz: «Die tragische Substanz – wie genetische Fehler Alterung und Krebs bewirken» null30 January, 7:00am–8:300pm nullUniversity of Zurich, Main Building, Aula (G-201), nullRämistrasse 71, 8006 Zurich nullIn German null nullnullnullAward ceremony Charles Rodolphe Brupbacher Prize nullfor Cancer Research 2013 null31 January 2013, 5:00am–6:30pm nullUniversity Hospital Zurich, Hörsaal Ost, Gloriastrasse 29, 8091 Zurich null nullnullnullYoung Investigator Awards nullUp to five poster presenters may receive a Young Investigator Award. Awardees have to be not older than 35 years of age, first author and present at the meeting. null1 February 2013, 11:00am–12:00am nullUniversity Hospital Zurich, Hörsaal Ost, Gloriastrasse 29, 8091 Zurich null nullThe foundation: nullThe Charles Rodolphe Brupbacher Foundation was founded in 1991 by Mme. Frédérique Brupbacher in memory of her husband, Charles Rodolphe Brupbacher. The foundation is affiliated with the Faculty of Medicine of the University of Zurich. More information on the foundation is available at null www.brupbacher-foundation.org null